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Wakix (pitolisant)Point32Health

narcolepsy with cataplexy

Initial criteria

  • Prescribed by or in consultation with a neurologist or sleep specialist
  • For adults age ≥ 18 years: documented diagnosis of narcolepsy with cataplexy OR excessive daytime sleepiness associated with narcolepsy AND EITHER (inadequate response, adverse reaction, or contraindication to ALL of: modafinil OR armodafinil, stimulant medication, Sunosi) OR (new to plan and stable on Wakix ≥ 2 months prior to enrollment, excluding samples)
  • For pediatric age 6–17 years: documented diagnosis of excessive daytime sleepiness associated with narcolepsy AND trial and failure, inadequate response, intolerance, or contraindication to one stimulant medication

Reauthorization criteria

  • Documentation that patient experienced improvement from baseline based on a decrease in frequency of cataplexy attacks OR reduction in daytime sleepiness

Approval duration

12 months