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Wegovy (semaglutide)Point32Health

Secondary cardiovascular prevention in overweight or obesity

Initial criteria

  • Patient age ≥ 45 years
  • Established cardiovascular disease as evidenced by prior myocardial infarction, prior stroke, or peripheral arterial disease
  • BMI ≥ 27
  • Used as adjunct to lifestyle modification (dietary restriction, exercise, behavioral support, community-based program)
  • Patient on standard-of-care therapy from each of the following unless contraindicated or intolerant: cholesterol-lowering medication (e.g., statin), antihypertensive (e.g., ACE inhibitor, ARB, beta blocker), and antiplatelet agent (e.g., aspirin, clopidogrel)
  • No diagnosis of type 1 or type 2 diabetes
  • No NYHA class IV heart failure

Reauthorization criteria

  • Member adherent to therapy with consistent fills over past 4 months
  • Currently on a maintenance dose of 1.7 mg or 2.4 mg once weekly
  • Established cardiovascular disease as evidenced by prior myocardial infarction, prior stroke, or peripheral arterial disease
  • Used as adjunct to lifestyle modification (dietary restriction, exercise, behavioral support, community-based program)
  • Continues on standard-of-care therapy from each of the following unless contraindicated or intolerant: cholesterol-lowering medication, antihypertensive, and antiplatelet agent
  • No diagnosis of type 1 or type 2 diabetes
  • No NYHA class IV heart failure