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Yesintek (ustekinumab-kfce)Point32Health

Ulcerative Colitis

Initial criteria

  • Documented diagnosis of ulcerative colitis
  • Patient age ≥ 18 years
  • Prescribed by or in consultation with a gastroenterologist
  • Documentation of one (1) of the following:
  • a. Inadequate response or adverse reaction to a corticosteroid, a 5-aminosalycylate, 6-mercaptopurine, or methotrexate
  • b. Contraindication to corticosteroids, 5-aminosalycylates, 6-mercaptopurine, and methotrexate
  • c. The patient is moderate to high risk as evidenced by deep ulcers on colonoscopy, long segments of small and/or large bowel involvement, perianal disease, extra-intestinal manifestations (e.g., fever, weight loss, abdominal pain, intermittent nausea/vomiting), history of bowel resections, or recent hospitalization for the disease
  • d. Previous treatment with a biologic agent indicated for the requested use
  • e. The patient is new to the plan and has been stable on the requested agent prior to enrollment