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Zokinvy (lonafarnib)Point32Health

Processing-deficient Progeroid Laminopathies

Initial criteria

  • Documented diagnosis of processing-deficient Progeroid Laminopathies
  • The patient is age ≥ 12 months
  • Prescribed by or in consultation with a specialist in progeria, genetics, or metabolic disorders
  • Documented body surface area ≥ 0.39 m²
  • Documentation of one of the following: heterozygous LMNA mutation with progerin-like protein accumulation OR homozygous or compound heterozygous ZMPSTE24 mutations