Amitiza (lubiprostone) — United Healthcare

Initial criteria

• Diagnosis of chronic idiopathic constipation OR
• Diagnosis of irritable bowel syndrome with constipation AND patient was female at birth OR
• Diagnosis of opioid-induced constipation in patients being treated for chronic, non-cancer pain OR
• Diagnosis of opioid-induced constipation in patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation

Reauthorization criteria

• Documentation of positive clinical response to therapy

Approval duration

12 months