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Ayvakit (avapritinib)United Healthcare

Myeloid/Lymphoid Neoplasms with eosinophilia

Initial criteria

  • Diagnosis of myeloid/lymphoid neoplasms with eosinophilia
  • Presence of a FIP1L1-PDGFRA rearrangement
  • Presence of a PDGFRA D842V mutation

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Ayvakit therapy

Approval duration

12 months