Skip to content
The Policy VaultThe Policy Vault

Cobenfy (xanomeline and trospium chloride)United Healthcare

schizophrenia

Preferred products

  • aripiprazole
  • olanzapine
  • quetiapine IR or ER
  • risperidone
  • ziprasidone

Initial criteria

  • Diagnosis of schizophrenia AND history of failure, contraindication, or intolerance to three of the following (document drug, date, and duration): aripiprazole (generic Abilify), olanzapine (generic Zyprexa), quetiapine IR or ER (generic Seroquel or Seroquel XR), risperidone (generic Risperdal), ziprasidone (generic Geodon)
  • OR treatment with Cobenfy was initiated at a recent behavioral inpatient admission (discharge within past 3 months) AND member is currently stable on therapy (document date of discharge)
  • OR member is new to the plan and currently stabilized on Cobenfy (coverage effective date ≤ 120 days)

Reauthorization criteria

  • Documentation of a positive clinical response to therapy

Approval duration

12 months