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Ebglyss (lebrikizumab-lbkz)United Healthcare

moderate to severe chronic atopic dermatitis

Preferred products

  • Elocon (mometasone furoate)
  • Synalar (fluocinolone acetonide)
  • Lidex (fluocinonide)
  • Elidel (pimecrolimus)
  • Protopic (tacrolimus)
  • Eucrisa (crisaborole)

Initial criteria

  • Diagnosis of moderate to severe chronic atopic dermatitis
  • History of failure, contraindication, or intolerance to two of the following therapeutic classes of topical therapies (document drug, date of trial, and/or contraindication): (a) Medium, high, or very-high potency topical corticosteroid [e.g., Elocon (mometasone furoate), Synalar (fluocinolone acetonide), Lidex (fluocinonide)] (b) Topical calcineurin inhibitor [e.g., Elidel (pimecrolimus), Protopic (tacrolimus)] (c) Eucrisa (crisaborole)
  • Patient is not receiving Ebglyss in combination with either of the following: (a) Biologic immunomodulator [e.g., Adbry (tralokinumab-ldrm), Dupixent (dupilumab)] (b) Janus kinase inhibitor [e.g., Cibinqo (abrocitinib), Opzelura (topical ruxolitinib), Rinvoq (upadacitinib), Xeljanz/XR (tofacitinib)]
  • Prescribed by one of the following: (a) Dermatologist (b) Allergist (c) Immunologist

Reauthorization criteria

  • Documentation of positive clinical response to Ebglyss therapy
  • Patient is not receiving Ebglyss in combination with either of the following: (a) Biologic immunomodulator [e.g., Adbry (tralokinumab-ldrm), Dupixent (dupilumab)] (b) Janus kinase inhibitor [e.g., Cibinqo (abrocitinib), Opzelura (topical ruxolitinib), Rinvoq (upadacitinib), Xeljanz/XR (tofacitinib)]
  • Prescribed by one of the following: (a) Dermatologist (b) Allergist (c) Immunologist

Approval duration

12 months