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Envarsus XR (tacrolimus extended-release tablets)United Healthcare

Prophylaxis of organ rejection in kidney transplant recipients

Preferred products

  • tacrolimus immediate-release

Initial criteria

  • Patient is the recipient of a kidney transplant
  • AND One of the following: (1) Provider attests that the patient is not an appropriate candidate for immediate-release tacrolimus based on one of the following: i. Unable to achieve or maintain an appropriate therapeutic drug level with immediate-release tacrolimus ii. In the provider’s expert opinion, the patient would be unable to achieve or maintain an appropriate therapeutic drug level with immediate-release tacrolimus OR (2) Patient is currently on Envarsus XR therapy and the provider attests that switching therapy would be clinically inappropriate
  • AND Envarsus XR will be used in combination with other immunosuppressant medications (e.g., mycophenolate, azathioprine, corticosteroids) to prevent organ rejection in kidney transplant recipients
  • AND Prescribed by or in consultation with a nephrologist or transplant specialist

Approval duration

12 months