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GrastekUnited Healthcare

moderate to severe grass pollen-induced allergic rhinitis

Initial criteria

  • Diagnosis of moderate to severe grass pollen-induced allergic rhinitis defined by symptoms severe enough to interfere with quality of life (e.g., sleep disturbances; impairment of daily, sport, or leisure activities; impairment of school or work performance)
  • Diagnosis confirmed by one of the following: Positive skin test to Timothy grass or cross-reactive grass pollens (e.g., Sweet Vernal, Orchard/Cocksfoot, Perennial Rye, Kentucky blue/June grass, Meadow Fescue, or Redtop) OR in vitro testing for pollen-specific IgE antibodies for Timothy grass or cross-reactive grass pollens (e.g., Sweet Vernal, Orchard/Cocksfoot, Perennial Rye, Kentucky blue/June grass, Meadow Fescue, or Redtop)
  • Treatment is started or will be started at least 12 weeks before the beginning of the grass pollen season
  • History of failure, contraindication, or intolerance to two of the following: oral antihistamine [e.g., cetirizine (Zyrtec)] AND/OR intranasal antihistamine [e.g., azelastine (Astelin)] AND/OR intranasal corticosteroid [e.g., fluticasone (Flonase)] AND/OR leukotriene inhibitor [e.g., montelukast (Singulair)]
  • Not received in combination with similar cross-reactive grass pollen immunotherapy (e.g., Oralair)
  • Patient does not have unstable and/or uncontrolled asthma
  • Prescribed by or in consultation with a specialist in allergy and immunology

Reauthorization criteria

  • Documentation of positive clinical response to Grastek therapy

Approval duration

12 months