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The Policy VaultThe Policy Vault

Kalydeco (ivacaftor)United Healthcare

Cystic fibrosis (CF) in patients aged 1 month and older who have at least one mutation in the CFTR gene that is responsive to ivacaftor based on clinical and/or in vitro assay data

Initial criteria

  • Diagnosis of cystic fibrosis (CF)
  • Submission of laboratory results confirming that patient has at least one of the CFTR gene mutations responsive to Kalydeco as listed in the Prescribing Information
  • Prescribed by or in consultation with a provider who specializes in the treatment of CF

Reauthorization criteria

  • Documentation of positive clinical response to Kalydeco therapy (e.g., improved lung function, stable lung function)

Approval duration

12 months