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Koselugo (selumetinib)United Healthcare

NF-1 mutated glioma

Initial criteria

  • One of the following:
  • a. Circumscribed glioma with presence of BRAF fusion or BRAF V600E activating mutations
  • b. NF-1 mutated glioma
  • Disease is recurrent or progressive
  • Used as monotherapy

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Koselugo therapy

Approval duration

12 months