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Kuvan (sapropterin dihydrochloride)United Healthcare

phenylketonuria (PKU)

Initial criteria

  • Diagnosis of phenylketonuria (PKU)
  • AND Patient is actively on a Phe-restricted diet
  • AND Patient is not receiving the requested medication in combination with Palynziq (pegvaliase-pqpz)

Reauthorization criteria

  • Patient is actively on a Phe-restricted diet
  • AND Blood Phe levels continue to remain lower than baseline level
  • AND Patient is not receiving the requested medication in combination with Palynziq (pegvaliase-pqpz)

Approval duration

12 months