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Lazcluze (lazertinib)United Healthcare

Non-small cell lung cancer (NSCLC) with EGFR exon 19 deletions or exon 21 L858R substitution mutations

Initial criteria

  • Diagnosis of non-small cell lung cancer (NSCLC)
  • Disease is recurrent OR advanced OR metastatic
  • Disease is positive for one of the following: EGFR exon 19 deletion OR EGFR exon 21 L858R mutation
  • Used in combination with Rybrevant (amivantamab-vmjw)

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Lazcluze therapy

Approval duration

12 months