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Lumakras (sotorasib)United Healthcare

rectal cancer

Initial criteria

  • Diagnosis of rectal cancer
  • Tumor is KRAS G12C-mutation positive
  • Patient has received at least one prior systemic therapy (e.g., immune checkpoint inhibitor, platinum-based chemotherapy)

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Lumakras therapy

Approval duration

12 months