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mifepristoneUnited Healthcare

control of hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing’s syndrome who have type 2 diabetes mellitus or glucose intolerance and who failed surgery or are not candidates for surgery

Initial criteria

  • Diagnosis of endogenous Cushing’s syndrome (i.e., hypercortisolism is not a result of chronic administration of high dose glucocorticoids)
  • AND one of the following: Diagnosis of type 2 diabetes mellitus OR Diagnosis of glucose intolerance
  • AND one of the following: Patient has failed surgery OR Patient is not a candidate for surgery

Reauthorization criteria

  • Documentation of a positive clinical response while on Korlym therapy

Approval duration

12 months