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Nexavar (sorafenib tosylate)United Healthcare

acute myeloid leukemia (AML)

Preferred products

  • Vidaza (azacitidine)
  • Dacogen (decitabine)

Initial criteria

  • Diagnosis of acute myeloid leukemia (AML)
  • AND Patient has FLT3‑ITD mutation‑positive disease
  • AND Patient has relapsed or refractory disease
  • AND Used in combination with Vidaza (azacitidine) OR Dacogen (decitabine)
  • AND Patient is unable to tolerate more aggressive treatment regimens

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Nexavar therapy

Approval duration

12 months