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Nubeqa (darolutamide)United Healthcare

non-metastatic castration-resistant prostate cancer (nmCRPC)

Initial criteria

  • Diagnosis of prostate cancer
  • AND one of the following: (a) Disease is non-metastatic AND castration-resistant OR (b) Disease is metastatic AND castration-sensitive
  • AND one of the following: (a) Used in combination with a gonadotropin-releasing hormone (GnRH) analog [e.g., Lupron (leuprolide), Zoladex (goserelin), Trelstar (triptorelin), Vantas (histrelin), Firmagon (degarelix)] OR (b) Patient has had a bilateral orchiectomy
  • For patients less than 19 years of age: Patient is less than 19 years of age OR NCCN Compendium indication with Category of Evidence and Consensus 1, 2A, or 2B

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Nubeqa therapy

Approval duration

12 months