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Pomalyst (pomalidomide)United Healthcare

Multiple Myeloma

Initial criteria

  • Diagnosis of multiple myeloma
  • AND
  • One of the following:
  • History of failure, contraindication, or intolerance to one of the following:
  • Immunomodulatory agent [e.g., Revlimid (lenalidomide)]
  • Proteasome inhibitor [e.g., Velcade (bortezomib)]
  • Anti CD-38 therapy [e.g., Darzalex (daratumumab), Sarclisa (isatuximab)]
  • OR
  • Induction therapy for the management of POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes) syndrome

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Pomalyst therapy

Approval duration

12 months