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Prevymis (letermovir)United Healthcare

Cytomegalovirus (CMV) prophylaxis in recipients of allogeneic hematopoietic stem cell transplant

Initial criteria

  • EITHER of the following:
  • 1) ALL of the following:
  • - Patient is a recipient of an allogeneic hematopoietic stem cell transplant
  • - AND - Patient is CMV-seropositive
  • - AND - Provider attests that Prevymis will be initiated between Day 0 and Day 28 post-transplantation (before or after engraftment) and is prescribed as prophylaxis and not treatment of CMV infection
  • OR
  • 2) ALL of the following:
  • - Patient is a recipient of a kidney transplant
  • - AND - Patient is CMV-seronegative
  • - AND - Donor is CMV-seropositive
  • - AND - Provider attests that Prevymis will be initiated between Day 0 and Day 7 post-transplantation (before or after engraftment) and is prescribed as prophylaxis and not treatment of CMV infection

Reauthorization criteria

  • All requests for reauthorization will be denied; continuation requests must be submitted through the appeals process to UnitedHealthcare Pharmacy appeals for consideration.

Approval duration

9 months