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Scemblix (asciminib)United Healthcare

Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML)

Initial criteria

  • Diagnosis of chronic myeloid leukemia (CML)
  • AND Disease is Philadelphia chromosome (Ph+) or BCR:ABL1-positive
  • AND One of the following:
  • - Used in newly diagnosed chronic phase CML (CP-CML)
  • - OR Used in previously treated chronic phase CML (CP-CML)
  • - OR Used in chronic phase CML (CP-CML) positive for a T315I mutation
  • - OR Used in accelerated phase CML as primary treatment as a single agent

Reauthorization criteria

  • Patient does not show evidence of progressive disease while on Scemblix therapy

Approval duration

12 months