Signifor — United Healthcare
Cushing’s disease
Initial criteria
- Diagnosis of endogenous Cushing’s disease (i.e., hypercortisolism is not a result of chronic administration of high dose glucocorticoids)
 - AND
 - One of the following:
 - Pituitary surgery has not been curative for the patient
 - OR
 - Patient is not a candidate for pituitary surgery
 
Reauthorization criteria
- Documentation of positive clinical response to Signifor therapy
 
Approval duration
12 months