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Xphozah (tenapanor)United Healthcare

Chronic kidney disease (CKD) on dialysis with hyperphosphatemia

Preferred products

  • calcium acetate (generic PhosLo)
  • lanthanum carbonate (generic Fosenrol)
  • sevelamer carbonate (generic Renvela)
  • Velphoro (sucroferric oxyhydroxide)

Initial criteria

  • Diagnosis of chronic kidney disease (CKD)
  • Patient is receiving dialysis
  • Serum phosphorus > 6.5 mg/dL
  • Patient has had an inadequate response to a maximally tolerated dose of two of the following phosphate binders: calcium acetate (generic PhosLo), lanthanum carbonate (generic Fosenrol), sevelamer carbonate (generic Renvela), Velphoro (sucroferric oxyhydroxide)
  • Xphozah will be used as add-on therapy
  • Prescribed by or in consultation with a nephrologist

Reauthorization criteria

  • Documentation of positive clinical response to Xphozah therapy (e.g., reduction of serum phosphorus towards the normal range 3.5–5.5 mg/dL)
  • Prescribed by or in consultation with a nephrologist

Approval duration

12 months